Explore Project Topics on: Protective effect of hydroethanolic extract of buccholzia coriacea on lipopolysaccharide induced inflammatory liver injury

ABSTRACT   This study examined the nephrotic effect of Buchholzia coriacea formulated diet in sucrose-fed pregnant rats and their offspring. Buchholzia coriacea (B. coriacea) (family, capparidaceae ) is a perennial plant commonly known as wonderful kola . Seeds were obtained from ogbete main market, Enugu state, identified, dried and grounded... Continue Reading

ABSTRACT Among medicinal plants, Picralima nitida is well investigated and has been shown to possess renal and hepatoprotective activities. The present study was conducted to investigate the chemoprotective effect of methanol extract of Picralima nitida leaves on carbon tetrachloride-induced oxidative stress in albino rats. Thirty (30) Wistar... Continue Reading

Abstract Areca catechu (also known as betel nut) is a common masticatory in tropical and subtropical countries.  Its seeds contain condensed tannins (Procyanidins) called arecatannins, which are reported to be carcinogenic. Virgin Coconut Oil is a colourless to brown-yellow edible oil obtained from fresh, mature kernel of Cocos nucifera... Continue Reading

ABSTRACT Ibuprofen, a strong analgesic and an anti-inflammatory drug used over a long period caused side effects such as peptic ulcer and constipation. Honeydew melon has been shown to possess anti-secretory, antiulcer and angiogenic. Hence, this study investigated the anti-ulcer effect of aqueous extract of honeydew melon on ibuprofen induced... Continue Reading

ABSTRACT  Cyclophosphamide (CP) is one of the most potent and widely used alkylating anticancer agents. Urotoxicity and myelosuppression is known as the most prevailing dose-limiting toxicity associated with CP. In the present study, the protective potential of Vernonia amygdalina and Ocimum gratissimum aqueous leaf extracts in CP-induced... Continue Reading

ABSTRACT Cyclophosphamide (CP) is one of the most potent and widely used alkylating anticancer agents. Urotoxicity and myelosuppression is known as the most prevailing dose-limiting toxicity associated with CP. In the present study, the protective potential of Vernonia amygdalina and Ocimum gratissimum aqueous leaf extracts in CP-induced... Continue Reading

ABSTRACT Kola bark extract have been widely used in tradition medicine for thousand of year, it improves liver functions and provides protection against high fat fed metabolic rats. Present investigations were carried out on the hepatoprotective role of Kola bark extract... Continue Reading

ABSTRACT This research was carried out to determine the effect of administration of  Achomanes Difformis (blume)  on liver functions in adult wistar rat, in which 20 adult wistar rats were purchased at the institute of advanced medical research and training (IMRAT), UCH, Ibadan. The rats were grouped into 4 in which there is a control group in... Continue Reading

Abstract Present investigations were carried out on the effect of ethanol extract of Desmodium velutinum stem on some liver enzymes of albino wistar rats fed with high fat from cow‟s brain. Twelve healthy albino wistar rats were divided into four groups. Group I rats were fed with balanced diet (normal feed, that is grower‟s mash) and tap... Continue Reading

Abstract Present investigations were carried out on the effect of ethanol extract of Desmodium velutinum stem on some liver enzymes of albino wistar rats fed with high fat from cow‟s brain. Twelve healthy albin groups. Group I rats were... Continue Reading

Abstract Present investigations were carried out on the effect of ethanol extract of Desmodium velutinum stem on some liver enzymes of albino wistar rats fed with high fat from cow‟s brain. Twelve healthy albino wistar rats were divided into four groups. Group I rats were fed with balanced diet (normal feed, that is grower‟s mash) and tap... Continue Reading

ABSTRACT The effect of aqueous leaves extract of Carica papaya (Linn) on some liver enzymesi.e; alanine aminotransferase ALT, aspartate aminotransferase AST, and alkaline phosphatase ALP, wasinvestigated.The phytochemical screening of the leaves extract of C.papaya was carried out at the beginning of the study.  Albino rats weighing between... Continue Reading

Abstract Present investigations were carried out on the effect of ethanol extract of Desmodium velutinum stem on some liver enzymes of albino wistar rats fed with high fat from cow‟s brain. Twelve healthy albino wistar rats were divided into four groups. Group I rats were fed with balanced diet (normal feed, that is grower‟s mash) and tap... Continue Reading

Abstract Present investigations were carried out on the effect of ethanol extract of Desmodium velutinum stem on some liver enzymes of albino wistar rats fed with high fat from cow‟s brain. Twelve healthy albino wistar rats were divided into four groups. Group I rats were fed with balanced diet (normal feed, that is grower‟s mash) and tap... Continue Reading

ABSTRACT Kola bark extract have been widely used in tradition medicine for thousand of year, it improves liver functions and provides protection against high fat fed metabolic rats. Present investigations were carried out on the hepatoprotective role of Kola bark extract meal treatment to high fat fed wistar rat. Healthy adult male wistar rats... Continue Reading

ABSTRACT Kola bark extract have been widely used in tradition medicine for thousand of year, it improves liver functions and provides protection against high fat fed metabolic rats. Present investigations were carried out on the hepatoprotective role of Kola bark extract meal treatment to high fat fed wistar rat. Healthy adult male wistar rats... Continue Reading

ABSTRACT Kola bark extract have been widely used in tradition medicine for thousand of year, it improves liver functions and provides protection against high fat fed metabolic rats. Present investigations were carried out on the hepatoprotective role of Kola bark extract meal treatment to high fat fed wistar rat. Healthy adult male wistar rats... Continue Reading

ABSTRACT Kola bark extract have been widely used in tradition medicine for thousand of year, it improves liver functions and provides protection against high fat fed metabolic rats. Present investigations were carried out on the hepatoprotective role of Kola bark extract meal treatment to high fat fed wistar rat. Healthy adult male wistar rats... Continue Reading

ABSTRACT  Evidences have implicated free radicals or reactive oxygen species in mercuric chloride-induced nephrotoxicity. Diphenyl diselenide (PhSe)2, a simple and stable organoselenium compound, has been proposed as a good candidate for pharmacological and therapeutic purposes. This particular study was designed to investigate the protective... Continue Reading

ABSTRACT  Evidences have implicated free radicals or reactive oxygen species in mercuric chloride-induced nephrotoxicity. Diphenyl diselenide (PhSe)2, a simple and stable organoselenium compound, has been proposed as a good candidate for pharmacological and therapeutic purposes. This particular study was designed to investigate the protective... Continue Reading

A research on management of diabetes. ... Continue Reading

A research on management of diabetes. ... Continue Reading

A research on management of diabetes. ... Continue Reading

In recent years, there has been profound interest in the role of oxidative stress in the precipitation of pre- diabetic condition (1) and there are reports of oxidative stress increasing in patients with diabetes mellitus (2). Oxidative stress results when reactive forms of oxygen are produced faster than they can be safely neutralized by the body... Continue Reading

In recent years, there has been profound interest in the role of oxidative stress in the precipitation of pre- diabetic condition (1) and there are reports of oxidative stress increasing in patients with diabetes mellitus (2). Oxidative stress results when reactive forms of oxygen are produced faster than they can be safely neutralized by the body... Continue Reading

This research project studied the effect of ethanolic leaf extract of Dialium guineense Willd (Fabaceae) on oral glucose tolerance in mice and alloxan-induced diabetic female rats.  The ethanolic leaf extract was prepared by marcerating 500g of the dried, milled leaves of D. guineense in 3L of 96% ethanol in a suitable sized plastic bucket/bowl... Continue Reading

COMPARATIVE STUDY OF THE EFFECT OF ETHANOLIC EXTRACT OF Lonchocarpus cyanescens (ELU) AND Dialium guineense (ICHEKU) ON THE LIPID PROFILE OF STREPTOZOTOCIN INDUCED DIABETIC ALBINO RATS ABSTRACT This study was carried out to determine the effect of ethanoic extract of Lonchocarpus cyanescens and Dialium guineense on the lipid profile of... Continue Reading

This research project studied the effect of ethanolic leaf extract of Dialium guineense Willd (Fabaceae) on oral glucose tolerance in mice and alloxan-induced diabetic female rats.  The ethanolic leaf extract was prepared by marcerating 500g of the dried, milled leaves of D. guineense in 3L of 96% ethanol in a suitable sized plastic bucket/bowl... Continue Reading

ABTRACT This study evaluates the cardio protactive effect of N-hexane extract of Desmodium Velutinum stem on albino wister rat. Rats used in this study were grouped into four and each group was fed differentely. Rats in group one, three, and four wre fed with the aid of a syringe without needle with 6ml of the lipoprotein food mixture containing... Continue Reading

ABTRACT This study evaluates the cardio protactive effect of N-hexane extract of Desmodium Velutinum stem on albino wister rat. Rats used in this study were grouped into four and each group was fed differentely. Rats in group one, three, and four wre fed with the aid of a syringe without needle with 6ml of the lipoprotein food mixture containing... Continue Reading