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  CHAPTER ONE INTRODUCTION AND LITERATURE REVIEW 1.0 INTRODUCTION Nanoscience has been the subject of substantial research in recent years. It has been explored by researchers in various fields of science and technology (Kholoud et al. 2010). The novel properties of NPs have been exploited in a wide range of potential applications such as in... Continue Reading
ABSTRACT  Ten plant samples were screened for topical anti-inflammatory activity. PDI.ra/n hi~w,u leaf (Family: Commelinaceae) gave the highest activity. A gradient solvent extraction of the leaf will conducted using petroleum ether (40' - 60'). cliloroforcn and methanol respectivel~. The different fractions were tested for anti-~nflarnrnalot-y... Continue Reading
ABSTRACT Erlangea tomentosa is been used traditionally in the management of several diseases including pain and inflammation. However, their efficacy has not been scientifically validated. The aim of this study therefore is to investigate the analgesic and anti-inflammatory activities of the aqueous leaf extract. The plant materials were collected... Continue Reading
Abstract   The  immunomodulatory  effect  of  the  ethanolic  leaf  extract  of  Phyllantus  amarus  on  wistar  rats  was investigated. Twenty eight (28) male animals were used for the study. The animals were divided into four (4) groups of... Continue Reading
Abstract The immunomodulatory effect of the ethanolic leaf extract of Phyllantus amarus on wistar rats was investigated. Twenty eight (28) male animals were used for the study. The animals were divided into four (4) groups of seven (7) animals each. Group 1... Continue Reading
ABSTRACT The anxiolytic and antinociceptive properties of the leaf extract and fraction of Phyllanthus muellerianus Kuntze (Phyllanthaceae) were investigated.The extract (MME; 500.18 g; 10%w/w), obtained by cold maceration in 1:1 mixture of methylene chloride: methanol for 48 h, was fractionationed in a silica gel column which yielded the ethyl... Continue Reading
TABLE OF CONTENTS CONTENTS PAGE TITLE PAGE - - - - - - - - - i DECLARATION - - - - - - - - ii CERTIFICATION - - - - - - - - iii DEDICATION - - - - - - - - iv ACKNOWLEDGEMENT - - - - - - - v TABLE OF CONTENT - - - - - - - vi LIST OF TABLES - - - - - - - - ix LIST OF FIGURES - - - - - - - ix ABSTRACT - - - - - - - - - x CHAPTER ONE INTRODUCTION AND... Continue Reading
Pepper are subjected to many problems such as weeds and diseases like tobacco mosaic virus, damping off, blossom end rot, spotted wilt phytophthora root rot, cucumber virus, bacterial spot, Alternaria leaf spot and of cause Cercospora leaf spot. Therefore this study was conducted to determine the effect of rice husk extract on leaf spot disease of... Continue Reading
Abstract This study evaluated the use of the methanolic leaf extract of Palisota hirsuta in postsurgical wound management using different wound models in rats. It also assessed the antibacterial activity of the plant extract as well as the possible toxic effects on the liver, kidney and blood. The yield of the methanolic leaf extract of Palisota... Continue Reading
Plants have been utilized for medicinal reasons since the dawn of time. Pharmacologists and organic chemists have synthesized a wide range of intriguing chemical compounds from medicinal plants in recent decades, which have shown to be quite useful in the practice of optometry and medicine. There is now an increase in global demand for the use of... Continue Reading
ABSTRACT Objectives: to explore the anxiolytic activity of ethanolic leaf extract of culcasian scadens in experimental animal models . Methods:  The anxiolytic activity was examined by using the elevated plus maze (EPM) and open field test (OFT), hole board test and light and dark box exploration test. Twenty Swiss albino male mice were divided... Continue Reading
Pepper are subjected to many problems such as weeds and diseases like tobacco mosaic virus, damping off, blossom end rot, spotted wilt phytophthora root rot, cucumber virus, bacterial spot, Alternaria leaf spot and of cause Cercospora leaf spot. Therefore this study was conducted to determine the effect of rice husk extract on leaf spot disease of... Continue Reading
ABSTRACT Objectives: to explore the anxiolytic activity of ethanolic leaf extract of culcasian scadens in experimental animal models . Methods:  The anxiolytic activity was examined by using the elevated plus maze (EPM) and open field test (OFT), hole board test and light and dark box exploration test. Twenty Swiss albino male mice were divided... Continue Reading
TABLE OF CONTENTS CONTENTS PAGE TITLE PAGE---------i DECLARATION--------ii CERTIFICATION--------iii DEDICATION--------iv ACKNOWLEDGEMENT-------v TABLE OF CONTENT-------vi LIST OF TABLES--------ix LIST OF FIGURES-------ix ABSTRACT---------x CHAPTER ONE INTRODUCTION AND LITERATURE REVIEW 1.1 TRADITIONAL MEDICINE-------1 1.2 MODERN MEDICINE--------4... Continue Reading
ABSTRACT The effect of Ocimum tenuiflorum on hematological parameters in immunosuppressed albino rats was investigated in this study. The aqueous (AE) and methanol extract (ME) of the leaf were obtained. Acute toxicity study was done to determine the LD50 of the leaf extract. Rats of mixed sexes, aged 2- 3months, weighing 150 to 240 grams were... Continue Reading
The medicinal values of some species of Mistletoes ( Tapinanthus globiferus ) growing in the West African sub-region have been reviewed along with some considerations of their chemistries and local uses. Studies carried out revealed that mistletoes showed hypotensive, hypoglycemic etc. This present study was aimed at investigating some effects of... Continue Reading
ABSTRACT The methanol extract of Ocimum basilicum (Scent leaf) was greenish in colour and increases in concentration through evaporation process which turns the extract to thick and dark green colouration. The percentage parasitaemia growth increases consecutively for seven (7) days with 7th day result having the highest parasite growth of 18.73%.... Continue Reading
The medicinal values of some species of Mistletoes ( Tapinanthus globiferus ) growing in the West African sub-region have been reviewed along with some considerations of their chemistries and local uses. Studies carried out revealed that mistletoes showed hypotensive, hypoglycemic etc. This present study was aimed at investigating some effects of... Continue Reading
ABSTRACT The methanol extract of Ocimum basilicum (Scent leaf) was greenish in colour and increases in concentration through evaporation process which turns the extract to thick and dark green colouration. The percentage parasitaemia growth increases consecutively for seven (7) days with 7th day result having the highest parasite growth of 18.73%.... Continue Reading
THE INHIBITORY EFFECT OF ETHANOLIC EXTRACT OF MORINGA OLEIFERA LEAF ON THE CORROSION OF MILD STEEL IN 5 M AND 1 M HYDROCHLORIC ACID (HCl)   DEPARTMENT OF PURE AND APPLIED CHEMISTRY   ABSTRACT The extract of Moringa oleifera leaf in aqueous 5 M HCl and 1 M HCl was systematically investigated to ascertain its inhibitory effect on the corrosion of... Continue Reading
ABSTRACT Uvaria chamae P. Beauv is known to have various medicinal and therapeutic properties. The Biochemical and toxicological effects of the leaf extract were assessed in this study using Albino wistar rats. Acute toxicity test was performed on the rats to determine the LD50.Sub acute toxicity test was also carried out by oral administration of... Continue Reading
Abstract The research on Mucuna pruriens was to know its ameliorative efficacy on the kidney markers of malaria infected mice. The antimalaria effect was evaluated against Plasmodium berghei stain of 25 mice.The twenty five (25) adult albino mice of both sexes which weighed 20g-36g were grouped into five(1-5) of five mice per group which was used... Continue Reading
ABSTRACT  Landolphia owariensis P. Beauv (Apocynaceae) is a woody liane commonly used in Africa for the treatment of gonorrhea, worm infestation and malaria. The methanol leaf extract (ME) of L. owariensis was obtained by cold maceration and then fractionated into nhexane (nHF), ethylacetate (EF) and methanol (MF) fractions. The methanol extract... Continue Reading
ABSTRACT In the present study, the phytochemical composition, immunomodulatory, leukocyte mobilization, haematological and antihepatotoxic effects of the aqueous extract of  Senna   mimosoides  leaves were evaluated. The study also covered the effect of the extract on theactivity of lactase and the assessment of the damaging effect of carbon... Continue Reading
ABSTRACT The study was conducted to assess the antibacterial activity of Phyllanthus amarus (Schum and Thonn) extract against Salmonella typhi causative agent of typhoid fever at the laboratories of the Departments of Chemistry and Theoretical and Applied Biology of the College of Science, Kwame Nkrumah University of Science and Technology,... Continue Reading
ABSTRACT Locally brewed beer (sorghum beer) is an indigenous alcohol average. It is produced mainly from sorghum grain (Sorghum vulgare ) and the process of brewing involves malting, mashing, souring, fermentation and... Continue Reading
Abstract Piper  guineense   ( Uziza  in Igbo) is a medicinal plant whose leaves are commonly used as spices.   This study is to investigate the effects of the  ethanolic  leaf extracts of  P. guineense   on the h istology of the liver , liver biom arker enzymes  of  paraquat -induced Thirty (30) adult male  Wistar  rats w eighing... Continue Reading
ABSTRACT The study was conducted to assess the antibacterial activity of Phyllanthus amarus (Schum and Thonn) extract against Salmonella typhi causative agent of typhoid fever at the laboratories of the Departments of Chemistry and Theoretical and Applied Biology of the College of Science, Kwame Nkrumah University of Science and Technology,... Continue Reading
ABSTRACT Diabetic mellitus is a metabolic disorder resulting from a defect in insulin secretion , insulin action or both . The deficiency of insulin leads to chronic hyperglycemia with disturbances of carbohydrate , fats and protein metabolism . Kigelia Africana is a sausage tree known to have medicinal values. The aim of this work is to evaluate... Continue Reading